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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNJ5
All Species:
31.52
Human Site:
T263
Identified Species:
69.33
UniProt:
P48544
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48544
NP_000881.3
419
47669
T263
D
I
N
V
G
F
D
T
G
D
D
R
L
F
L
Chimpanzee
Pan troglodytes
XP_508857
330
37659
L200
P
K
K
R
A
E
T
L
M
F
S
N
N
A
V
Rhesus Macaque
Macaca mulatta
XP_001113289
429
48853
T273
D
I
N
V
G
F
D
T
G
D
D
R
L
F
L
Dog
Lupus familis
XP_546402
419
47408
T263
D
I
N
V
G
F
D
T
G
D
D
R
L
F
L
Cat
Felis silvestris
Mouse
Mus musculus
P48545
419
47571
T263
D
I
N
V
G
F
D
T
G
D
D
R
L
F
L
Rat
Rattus norvegicus
P48548
419
47764
T263
D
I
N
V
G
F
D
T
G
D
D
R
L
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509759
885
96895
T728
D
I
N
V
G
Y
Y
T
G
D
D
R
L
F
L
Chicken
Gallus gallus
Q90854
492
55398
L254
F
S
T
G
A
D
Q
L
F
L
V
S
P
L
T
Frog
Xenopus laevis
NP_001156864
429
49473
T285
D
I
N
V
G
F
D
T
G
D
D
R
L
F
L
Zebra Danio
Brachydanio rerio
XP_700619
425
48766
T264
D
I
N
I
G
F
D
T
G
D
D
R
L
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52192
505
57401
I287
E
M
K
V
G
P
S
I
A
D
D
D
R
L
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.1
96.2
94
N.A.
93.3
93.7
N.A.
36.6
48.9
73.4
72.7
N.A.
N.A.
N.A.
34.4
N.A.
Protein Similarity:
100
77.3
97.4
96.4
N.A.
95.9
96.4
N.A.
40.9
63.2
81.3
83
N.A.
N.A.
N.A.
52.2
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
86.6
0
100
93.3
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
93.3
0
100
100
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
19
0
0
0
10
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
73
0
0
0
0
10
64
0
0
82
82
10
0
0
0
% D
% Glu:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
64
0
0
10
10
0
0
0
73
10
% F
% Gly:
0
0
0
10
82
0
0
0
73
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
73
0
10
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
10
19
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
19
0
10
0
0
73
19
73
% L
% Met:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
73
0
0
0
0
0
0
0
0
10
10
0
0
% N
% Pro:
10
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
73
10
0
0
% R
% Ser:
0
10
0
0
0
0
10
0
0
0
10
10
0
0
0
% S
% Thr:
0
0
10
0
0
0
10
73
0
0
0
0
0
0
10
% T
% Val:
0
0
0
73
0
0
0
0
0
0
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _